Chronic Liver Disease Severity Classification
Classifies chronic liver disease severity into Class A (well-compensated), B (significant compromise) or C (decompensated cirrhosis). Widely used for surgical risk stratification and prognosis.
| Parameter | 1 point | 2 points | 3 points |
|---|---|---|---|
| Bilirubin (mg/dL) | < 2.0 | 2.0–3.0 | > 3.0 |
| Albumin (g/dL) | > 3.5 | 2.8–3.5 | < 2.8 |
| INR | < 1.7 | 1.7–2.3 | > 2.3 |
| Ascites | None | Mild (diuretic-responsive) | Moderate–severe or refractory |
| Encephalopathy | None | Grade I–II | Grade III–IV |
Total score = sum of 5 parameters. Range: 5–15 points. Some centres use PT prolongation instead of INR: <4s=1pt, 4–6s=2pt, >6s=3pt.
| Score | Class | Disease State | 1-Year Survival | 2-Year Survival |
|---|---|---|---|---|
| 5–6 | A | Well-compensated | ~100% | ~85% |
| 7–9 | B | Significant functional compromise | ~81% | ~57% |
| 10–15 | C | Decompensated cirrhosis | ~45% | ~35% |
| Class | Estimated Operative Mortality | Recommendation |
|---|---|---|
| A | 5–10% | Elective surgery acceptable with optimisation |
| B | 25–30% | High risk — consider only if unavoidable; optimise first |
| C | 60–80% | Surgery contraindicated except life-saving emergency |
Originally developed by Child and Turcotte (1964) and modified by Pugh (1973) to predict perioperative mortality in patients with cirrhosis undergoing porto-caval shunt surgery. It remains the most widely used clinical classification of liver disease severity in surgical and anaesthetic planning.