Child-Pugh Score

Chronic Liver Disease Severity Classification

Classifies chronic liver disease severity into Class A (well-compensated), B (significant compromise) or C (decompensated cirrhosis). Widely used for surgical risk stratification and prognosis.

HepatologyCirrhosisSurgical Risk
Child-Pugh Score Calculator
Quick reference: Bilirubin <2=1pt, 2–3=2pt, >3=3pt • Albumin >3.5=1pt, 2.8–3.5=2pt, <2.8=3pt • INR <1.7=1pt, 1.7–2.3=2pt, >2.3=3pt

Scoring Criteria

Parameter1 point2 points3 points
Bilirubin (mg/dL)< 2.02.0–3.0> 3.0
Albumin (g/dL)> 3.52.8–3.5< 2.8
INR< 1.71.7–2.3> 2.3
AscitesNoneMild (diuretic-responsive)Moderate–severe or refractory
EncephalopathyNoneGrade I–IIGrade III–IV

Total score = sum of 5 parameters. Range: 5–15 points. Some centres use PT prolongation instead of INR: <4s=1pt, 4–6s=2pt, >6s=3pt.

Interpretation

ScoreClassDisease State1-Year Survival2-Year Survival
5–6AWell-compensated~100%~85%
7–9BSignificant functional compromise~81%~57%
10–15CDecompensated cirrhosis~45%~35%

Surgical Risk (Cirrhotic Patients)

ClassEstimated Operative MortalityRecommendation
A5–10%Elective surgery acceptable with optimisation
B25–30%High risk — consider only if unavoidable; optimise first
C60–80%Surgery contraindicated except life-saving emergency

Clinical Application

Originally developed by Child and Turcotte (1964) and modified by Pugh (1973) to predict perioperative mortality in patients with cirrhosis undergoing porto-caval shunt surgery. It remains the most widely used clinical classification of liver disease severity in surgical and anaesthetic planning.

  • Surgical risk stratification: Standard tool for assessing fitness for elective surgery in cirrhotic patients, used alongside MELD for major hepatic and non-hepatic procedures
  • Hepatocellular carcinoma: BCLC staging and most HCC treatment algorithms require Child-Pugh classification — Class C generally excludes resection, ablation, and TACE
  • Primary biliary cholangitis & PSC: Used alongside disease-specific scores for transplant timing decisions
  • HVPG-guided therapy: Child-Pugh class informs risk of variceal bleeding in cirrhotic patients and guides prophylaxis
  • Drug dosing: Medication prescribing in hepatic impairment commonly references Child-Pugh class (A/B/C) for dose adjustments

Limitations

  • Subjective parameters (ascites and encephalopathy) introduce inter-observer variability
  • Ceiling effect — Class C covers a wide range of severity (score 10–15)
  • Less precise than MELD for predicting 90-day mortality on the transplant waiting list
  • Albumin and bilirubin affected by factors other than liver function (inflammation, haemolysis, nutritional state)
  • Does not incorporate renal function (creatinine/sodium), which strongly predicts outcomes in cirrhosis
  • PT/INR can be affected by vitamin K deficiency and anticoagulant use

References

  1. Child CG, Turcotte JG. Surgery and portal hypertension. In: The Liver and Portal Hypertension. Philadelphia: Saunders; 1964. pp 50–64.
  2. Pugh RN, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646–649.
  3. Garrison RN, et al. Clarification of risk factors for abdominal operations in patients with hepatic cirrhosis. Ann Surg. 1984;199(6):648–655.
  4. de Franchis R, et al. Baveno VII — Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959–974.
  5. Reissfelder C, et al. The EASL Clinical Practice Guidelines on the management of hepatocellular carcinoma. J Hepatol. 2018;69(1):182–236.

Related Calculators