Glasgow-Blatchford Score

Upper GI Bleeding Triage

Pre-endoscopy risk score for upper GI haemorrhage. The only validated score to identify very-low-risk patients (score 0) who can be safely managed as outpatients without urgent endoscopy.

GastroenterologyUpper GI BleedingEmergency
Glasgow-Blatchford Score
Additional risk factors (tick all that apply)
Enter values above

Scoring Components

ComponentThresholdPoints
BUN (mg/dL)< 18.20
18.2 – 22.42
22.4 – 28.03
28.0 – 70.04
BUN ≥ 706
Hb — Men (g/dL)≥ 13.00
12.0 – 12.91
10.0 – 11.93
Hb Men < 10.0 / Women < 10.06
Hb — Women 10.0–11.91
SBP (mmHg)≥ 1100
100 – 1091
90 – 992
SBP < 903
HR ≥ 100 bpm+1
Melena at presentation+1
Syncope+2
Liver disease (known)+2
Cardiac failure (known)+2

Interpretation

GBSRisk LevelClinical Recommendation
0Very LowSafe for outpatient management; early discharge without endoscopy may be appropriate (BSG 2019, NICE)
1–2LowInpatient or early outpatient endoscopy; monitor closely
3–5ModerateInpatient endoscopy within 24 hours
≥ 6HighUrgent endoscopy; likely to require intervention
≥ 12Very HighEmergency endoscopy; very high probability of needing intervention or transfusion

Clinical Application

The GBS is the recommended pre-endoscopy triage tool for UGIB in BSG (2019), ACG (2021), and European Society of Gastrointestinal Endoscopy (ESGE) guidelines. It outperforms pre-endoscopy Rockall for identifying patients safe for discharge.

  • Score 0: AUC ~0.93 for identifying patients who can be managed without urgent endoscopy. Approximately 15–20% of UGIB presentations score 0.
  • Discriminates well for need for transfusion, endoscopic intervention, re-bleeding, and in-hospital mortality.
  • Important: GBS does not replace clinical assessment — active haematemesis, haemodynamic instability, or clinical concern warrants endoscopy regardless of score.
  • Post-endoscopy: Once endoscopy is completed, use the full Rockall Score to further risk stratify for re-bleeding and mortality.

Evidence & Validation

The GBS was derived by Blatchford et al. (2000) from 1748 consecutive UGIB admissions in Glasgow. It was specifically designed as a pre-endoscopy triage tool, unlike the Rockall score which requires endoscopy findings.

Multiple validation studies (Cheng et al. 2012, Stanley et al. 2012, Bessa et al. 2011) confirmed its c-statistic of 0.86–0.92 for predicting clinical intervention. The 2015 BSG meta-analysis (Laursen et al.) recommended GBS ≤1 as the threshold for safe early discharge with NPV >99%.

Limitations

  • Pre-endoscopy only — does not incorporate endoscopic findings
  • BUN can be elevated in renal failure, high-protein intake, or dehydration unrelated to GI bleeding
  • Does not account for anticoagulant use, which significantly affects re-bleeding risk
  • Less useful in patients with chronic renal failure (creatinine-adjusted BUN thresholds may be needed)
  • Clinical factors like frailty, social circumstances, and patient preference should also guide discharge decisions at score 0–1

References

  1. Blatchford O, et al. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000;356(9238):1318–1321.
  2. Stanley AJ, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage (GBS ≤1). Lancet. 2009;373(9657):42–47.
  3. Laursen SB, et al. The Glasgow-Blatchford Score is the most accurate assessment of patients with upper-GI bleeding. Clin Gastroenterol Hepatol. 2012;10(10):1130–1135.
  4. BSG. Guidelines on the management of acute upper gastrointestinal bleeding. Gut. 2019;68(Suppl 1):1–i57.
  5. Laine L, et al. ACG Clinical Guideline: Upper gastrointestinal and ulcer bleeding. Am J Gastroenterol. 2021;116(5):899–917.

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